Pressure overload is a condition characterized by an increased workload on the heart, leading to an increase in blood pressure and potential damage to the heart muscle. This condition can be caused by various factors such as hypertension, valve disorders, or narrowing of arteries. Research in the area of pressure overload aims to understand the underlying mechanisms of this condition, develop effective treatments, and improve outcomes for patients with heart conditions related to increased pressure on the heart. Studies in this area often focus on identifying biomarkers, developing novel therapeutic strategies, and exploring the impact of pressure overload on cardiac function and structure.